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A mitochondrial transport protein promotes carnitine synthesis in mice when fat consumption is needed. Learn more in a new SciencePerspective: https://scim.ag/4rpAJQt
Because exercise naturally activates many of these metabolic pathways, SLU-PP-332 has gained attention in preclinical research as an exercise-mimetic compound —a tool used to study how ERR activation may reproduce select molecular signatures associated with endurance-style exercise
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Chemicals NNMT inhibitors and standards for LC/MS/MS studies were purchased from established commercial suppliers or synthesized in-house by established synthetic schemes as described previously.[17] SAM, NA, 1-MQ, 1,8-diMQ, NAD + , and 6-chloro nicotinamide (6-CN) were obtained from Sigma-Aldrich (St